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・ Cyclidia sericea
・ Cyclidia substigmaria
・ Cyclidia tetraspota
・ Cyclidiinae
・ Cyclin
・ Cyclin A
・ Cyclin A1
・ Cyclin A2
・ Cyclin B
・ Cyclin B1
・ Cyclin B2
・ Cyclin D
・ Cyclin D/Cdk4
・ Cyclin D1
・ Cyclin D2
Cyclin D3
・ Cyclin E
・ Cyclin E1
・ Cyclin E2
・ Cyclin H
・ Cyclin K
・ Cyclin O
・ Cyclin T1
・ Cyclin T2
・ Cyclin-dependent kinase
・ Cyclin-dependent kinase 1
・ Cyclin-dependent kinase 10
・ Cyclin-dependent kinase 2
・ Cyclin-dependent kinase 3
・ Cyclin-dependent kinase 4


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Cyclin D3 : ウィキペディア英語版
Cyclin D3

G1/S-specific cyclin-D3 is a protein that in humans is encoded by the ''CCND3'' gene.
== Function ==

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=896 )

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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